Physicochemical and pharmacokinetic parameters in drug selection and loading for transdermal drug delivery

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Electrospun polymeric nanofibers for transdermal drug delivery

Conventional transdermal drug delivery systems (TDDS) have been designed for drug delivery through the skin. These systems use the permeability property of stratum corneum, the outermost surface layer of the skin. Applying polymeric micro and nanofibers in drug delivery has recently attracted great attention and the electrospinning technique is the preferred method for polymeric micro-nanofiber...

متن کامل

Novel transdermal drug delivery systems

Background and aim: Eczema is a common inflammatory skin disease. Although history and physical examination are important in diagnosis of allergen, because of extent of environmental allergens, those are not simply recognized. The objective of this study was to determine allergens in patients with contact or atopic dermatitis referred to Razi hospital.Materials and Meth...

متن کامل

SKIN-CAD®: Pharmacokinetic Model for Transdermal Drug Delivery

Pharmacokinetic-pharmacodynamic (PK-PD) models for percutaneous absorption are useful in evaluating the clinical performance and optimizing the design of transdermal therapeutic systems [1, 2]. Diffusion models have been developed in order to analyze diffusivity and partitioning of drugs in the skin [3, 4]. However, there are few in silico approaches for predicting the clinical performance as w...

متن کامل

A review of the microneedles for transdermal drug delivery

Microneedles consist of micron-sized projections similar to needles. They are capable of piercing through the stratum corneum and increase the permeation of active ingredients. Besides active pharmaceutical ingredients, microneedles can also deliver cosmetic agents, biotherapeutics like insulin and vaccines and also are used in diagnostic purposes. This article examines the types of microneedle...

متن کامل

Microneedles for transdermal drug delivery.

The success of transdermal drug delivery has been severely limited by the inability of most drugs to enter the skin at therapeutically useful rates. Recently, the use of micron-scale needles in increasing skin permeability has been proposed and shown to dramatically increase transdermal delivery, especially for macromolecules. Using the tools of the microelectronics industry, microneedles have ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2008

ISSN: 0250-474X

DOI: 10.4103/0250-474x.40340